Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.70 |
| ▸ | HPGDS | O60760 | 4/20 | 0.61 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31255644 | 0.94 | CRBN (0.62) | CRBNHPGDSDDB1ALDH1A1CHRM2 | |
| SCHEMBL30805430 | 0.93 | CRBN (0.69) | CRBNHPGDSDDB1ALDH1A1CHRM2 | |
| SCHEMBL27008964 | 0.91 | CRBN (0.69) | CRBNHPGDSDDB1ALDH1A1CHRM2 | |
| SCHEMBL30441764 | 0.91 | CRBN (0.69) | CRBNHPGDSDDB1ALDH1A1CHRM2 | |
| SCHEMBL25265619 | 0.91 | CRBN (0.69) | CRBNHPGDSDDB1ALDH1A1CHRM2 | |
| SCHEMBL25201075 | 0.91 | CRBN (0.69) | CRBNHPGDSDDB1ALDH1A1CHRM2 | |
| SCHEMBL29132193 | 0.91 | CRBN (0.63) | CRBNHPGDSDDB1ALDH1A1CHRM2 | |
| SCHEMBL29927465 | 0.91 | CRBN (0.63) | CRBNHPGDSDDB1ALDH1A1CHRM2 | |
| SCHEMBL30726376 | 0.90 | CRBN (0.67) | CRBNHPGDSDDB1ALDH1A1CHRM2 | |
| SCHEMBL29132197 | 0.89 | CRBN (0.61) | CRBNHPGDSDDB1ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023077441-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2023-05-11 | — | — | WO | disclosed |