Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL31255644

O=C(O)C(F)(F)F.O=C1CCC(N2C(=O)c3ccc(N4CCN(C(=O)C5CCNCC5)CC4)cc3C2=O)C(=O)N1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 18/20 0.62
▸ HPGDS O60760 4/20 0.57
▸ DDB1 Q16531 10/20 0.49
▸ ALDH1A1 P00352 1/20 0.45
▸ CHRM2 P08172 1/20 0.45
▸ OPRM1 P35372 1/20 0.45
▸ IKZF3 Q9UKT9 1/20 0.45
▸ CYP1A2 P05177 1/20 0.45
▸ TSHR P16473 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ PLK4 O00444 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25550938 0.94 CRBN (0.70) CRBNHPGDSDDB1ALDH1A1CHRM2
Trifluoroacetic Acid SCHEMBL27039598 0.92 CRBN (0.60) CRBNHPGDSDDB1ALDH1A1CHRM2
Trifluoroacetic Acid SCHEMBL23860255 0.90 CRBN (0.70) CRBNHPGDSDDB1ALDH1A1CHRM2
Trifluoroacetic Acid SCHEMBL28491667 0.88 CRBN (0.69) CRBNHPGDSDDB1ALDH1A1CHRM2
SCHEMBL30441764 0.87 CRBN (0.69) CRBNHPGDSDDB1ALDH1A1CHRM2
SCHEMBL30805430 0.87 CRBN (0.69) CRBNHPGDSDDB1ALDH1A1CHRM2
SCHEMBL27008964 0.87 CRBN (0.69) CRBNHPGDSDDB1ALDH1A1CHRM2
SCHEMBL25265619 0.87 CRBN (0.69) CRBNHPGDSDDB1ALDH1A1CHRM2
SCHEMBL25201075 0.87 CRBN (0.69) CRBNHPGDSDDB1ALDH1A1CHRM2
Trifluoroacetic Acid SCHEMBL23705577 0.86 CRBN (0.60) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720044-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD Beactica Therapeutics AB (SE) 2026-04-08 — — EP disclosed
WO-2024240840-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD BEACTICA THERAPEUTICS AB (SE) 2024-11-28 — — WO disclosed
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