Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23583700 | 1.00 | CHRM3 (0.32) | CHRM3PDK1PDK2PDK3 | |
| SCHEMBL24176143 | 1.00 | CHRM3 (0.32) | CHRM3PDK1PDK2PDK3 | |
| SCHEMBL1106480 | 0.88 | CHRM3 (0.41) | CHRM3 | |
| SCHEMBL278415 | 0.88 | CHRM3 (0.41) | CHRM3 | |
| SCHEMBL57317 | 0.88 | CHRM3 (0.41) | CHRM3 | |
| SCHEMBL16812144 | 0.86 | CHRM3 (0.38) | CHRM3 | |
| SCHEMBL21625307 | 0.81 | CHRM3 (0.32) | CHRM3 | |
| SCHEMBL21625301 | 0.81 | CHRM3 (0.32) | CHRM3 | |
| SCHEMBL22388196 | 0.78 | CHRM3 (0.30) | CHRM3 | |
| SCHEMBL18471532 | 0.76 | PDK1 (0.51) | PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086383-A1 | SELECT KRAS G12C INHIBITORS AND USES THEREOF | 1200 PHARMA LLC (US) | 2023-05-19 | — | — | WO | disclosed |