Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557143 | 0.83 | HSD17B10 (0.47) | SLC6A4SLC6A2SLC6A3HRH3HTR2A | |
| SCHEMBL15270946 | 0.80 | KDM4E (0.50) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL31053280 | 0.80 | LMNA (0.50) | MAPTTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31053274 | 0.80 | KDM4E (0.50) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11965268 | 0.80 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3HRH3HTR2A | |
| SCHEMBL11965266 | 0.80 | PTGDR2 (0.43) | SLC6A4SLC6A2SLC6A3HRH3HTR2A | |
| SCHEMBL2558706 | 0.79 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3HTR2AMAPT | |
| SCHEMBL2557947 | 0.79 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HRH3HTR2A | |
| SCHEMBL1643221 | 0.78 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL1643557 | 0.78 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3HRH3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130741-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |