SCHEMBL25560565

SCHEMBL25560565

O=C(O)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C(F)(F)F)c1

nearest known ligand 0.74

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RXRA P19793 5/20 0.74
RXRB P28702 5/20 0.74
RXRG P48443 4/20 0.74
DHODH Q02127 1/20 0.64
P2RY14 Q15391 8/20 0.58
SLC6A2 P23975 1/20 0.57
SRD5A2 P31213 1/20 0.55
PPARA Q07869 1/20 0.51
MAP4K4 O95819 1/20 0.50
CYP2C8 P10632 1/20 0.50
OPRD1 P41143 2/20 0.49
KCNH2 Q12809 1/20 0.49
SIGMAR1 Q99720 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30469526 1.00 RXRA (0.74) RXRARXRBRXRGDHODHP2RY14
SCHEMBL3062844 0.93 DHODH (0.72) RXRARXRBRXRGDHODHP2RY14
SCHEMBL23326915 0.93 DHODH (0.72) RXRARXRBRXRGDHODHP2RY14
SCHEMBL21462308 0.90 RXRA (0.70) RXRARXRBRXRGDHODHP2RY14
SCHEMBL121358 0.89 RXRA (0.69) RXRARXRBRXRGDHODHP2RY14
SCHEMBL17048588 0.89 RXRA (0.72) RXRARXRBRXRGDHODHP2RY14
SCHEMBL27484945 0.88 RXRA (0.63) RXRARXRBRXRGDHODHP2RY14
Hydrochloric Acid SCHEMBL5371724 0.87 RXRA (0.61) RXRARXRBRXRGDHODHP2RY14
SCHEMBL2554127 0.85 RXRA (0.64) RXRARXRBRXRGDHODHP2RY14
SCHEMBL23698041 0.85 RXRA (1.00) RXRARXRBRXRGDHODHSRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3814332-B1 PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2023-06-07 EP disclosed