Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22520769 | 0.87 | CHRM5 (0.43) | HRH3CHRM5ADRA2CACHEKCNH2 | |
| SCHEMBL14453909 | 0.85 | CHRM5 (0.41) | HRH3CHRM5ADRA2CACHEKCNH2 | |
| SCHEMBL24233173 | 0.83 | ACHE (0.44) | HRH3CHRM5ADRA2CACHEKCNH2 | |
| SCHEMBL10104076 | 0.83 | CHRM5 (0.56) | HRH3CHRM5ADRA2CACHEGAA | |
| SCHEMBL13860741 | 0.83 | CHRM5 (0.50) | HRH3CHRM5ADRA2CACHEKCNH2 | |
| SCHEMBL15242459 | 0.82 | CHRM5 (0.59) | HRH3CHRM5ADRA2CACHEGAA | |
| SCHEMBL13300929 | 0.80 | HRH3 (0.46) | HRH3CHRM5ADRA2CACHEKCNH2 | |
| SCHEMBL25466871 | 0.80 | ACHE (0.41) | HRH3CHRM5ADRA2CACHEKCNH2 | |
| SCHEMBL23484949 | 0.80 | ACHE (0.60) | HRH3CHRM5ADRA2CACHETLR9 | |
| SCHEMBL25480261 | 0.79 | HRH3 (0.36) | HRH3CHRM5ADRA2CACHEKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096995-A1 | COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED N-(2-CHLORO-6-METHYLPHENYL)-2-((6-(6-MEMBERED HETEROCYCLOALKYL)-2-METHYLPYRIMIDIN-4-YL)AMINO)THIAZOLE-5-CARBOXAMIDE ANALOGUES | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2023-06-01 | — | — | WO | disclosed |