Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.50 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.44 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.44 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.41 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19993815 | 0.89 | ENPP1 (0.54) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL23171493 | 0.86 | ENPP1 (0.49) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL19050103 | 0.76 | ENPP1 (0.41) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL19536267 | 0.76 | ENPP1 (0.41) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL14853803 | 0.74 | ENPP1 (0.61) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL19993770 | 0.74 | ENPP1 (0.50) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL26019458 | 0.74 | ENPP1 (0.52) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL23225617 | 0.73 | ENPP1 (0.39) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL17384900 | 0.73 | ENPP1 (0.47) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL5080093 | 0.72 | PI4KA (0.63) | PI4KAPI4K2BPI4K2API4KBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013340-B1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN BIOPHARMA INC (US) | 2023-06-07 | — | — | EP | disclosed |