Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.52 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 7/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.39 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.39 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853803 | 0.76 | ENPP1 (0.61) | ENPP1ENPP3P2RY1P2RY2P2RX1 | |
| SCHEMBL26972786 | 0.75 | TRPM2 (0.63) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| SCHEMBL16374060 | 0.74 | ENPP1 (0.57) | ENPP1ENPP3P2RY1P2RY2P2RX1 | |
| SCHEMBL25564637 | 0.74 | ENPP1 (0.50) | ENPP1ENPP3P2RY1P2RY2P2RX1 | |
| SCHEMBL21078479 | 0.73 | ENPP1 (0.61) | ENPP1ENPP3P2RY1P2RY2P2RX1 | |
| SCHEMBL19993815 | 0.73 | ENPP1 (0.54) | ENPP1ENPP3P2RY1P2RY2P2RX1 | |
| SCHEMBL26255660 | 0.73 | ADORA2A (0.45) | ALDH1A1SMN1; SMN2ADORA2AADORA2BADORA1 | |
| SCHEMBL19760468 | 0.71 | ENPP1 (0.53) | ENPP1ENPP3P2RY1P2RY2P2RX1 | |
| SCHEMBL23171493 | 0.71 | ENPP1 (0.49) | ENPP1ENPP3P2RY1P2RY2P2RX1 | |
| SCHEMBL20057109 | 0.70 | ADORA2A (0.51) | ENPP1ENPP3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11730712-B2 | Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease | ESPERVITA THERAPEUTICS, INC. (US) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11730712-B2 | Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease | CPT1A, PPARG, PC | ENPP1 3103/4885ENPP3 2881/4885P2RY1 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.