Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT7 | O95251 | 20/20 | 0.57 |
| ▸ | KAT6A | Q92794 | 20/20 | 0.57 |
| ▸ | KAT6B | Q8WYB5 | 11/20 | 0.57 |
| ▸ | KAT5 | Q92993 | 11/20 | 0.57 |
| ▸ | KAT8 | Q9H7Z6 | 11/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22817400 | 0.93 | KAT7 (0.63) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25564286 | 0.89 | KAT7 (0.51) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25564233 | 0.89 | KAT7 (0.57) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL26800993 | 0.83 | KAT7 (0.66) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL22817384 | 0.83 | KAT7 (0.66) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25564128 | 0.82 | KAT7 (0.58) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25561720 | 0.81 | KAT7 (0.80) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25563986 | 0.80 | KAT7 (0.62) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25561706 | 0.80 | KAT7 (0.85) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL22817393 | 0.79 | KAT7 (0.69) | KAT7KAT6AKAT6BKAT5KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088233-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-25 | — | — | WO | disclosed |