SCHEMBL26800993

SCHEMBL26800993

COc1ccc(OC)c([S+]([O-])Nc2noc3cc(Cn4cccn4)cc(OC)c23)c1

nearest known ligand 0.66

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KAT7 O95251 20/20 0.66
KAT6A Q92794 20/20 0.66
KAT6B Q8WYB5 13/20 0.66
KAT5 Q92993 13/20 0.66
KAT8 Q9H7Z6 13/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22817384 0.91 KAT7 (0.66) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817400 0.90 KAT7 (0.63) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25565403 0.84 KAT7 (0.56) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25564640 0.83 KAT7 (0.57) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25564233 0.83 KAT7 (0.57) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817394 0.82 KAT7 (0.67) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817393 0.82 KAT7 (0.69) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25563914 0.82 KAT7 (0.57) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817330 0.80 KAT7 (0.69) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25563986 0.80 KAT7 (0.62) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3986890-B1 BENZISOXAZOLE SULFONAMIDE DERIVATIVES PFIZER (US) 2023-11-15 EP disclosed