Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 8/20 | 0.35 |
| ▸ | KDR | P35968 | 8/20 | 0.35 |
| ▸ | FLT3 | P36888 | 8/20 | 0.35 |
| ▸ | LCK | P06239 | 5/20 | 0.35 |
| ▸ | LYN | P07948 | 5/20 | 0.35 |
| ▸ | FLT4 | P35916 | 5/20 | 0.35 |
| ▸ | BLK | P51451 | 5/20 | 0.35 |
| ▸ | FYN | P06241 | 5/20 | 0.35 |
| ▸ | AURKA | O14965 | 4/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 4/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.35 |
| ▸ | RET | P07949 | 4/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27176104 | 0.78 | IDO1 (0.65) | IDO1ALDH1A1USP2HPGDHSD17B10 | |
| SCHEMBL26074232 | 0.77 | IDO1 (0.46) | IDO1ALDH1A1USP2HPGDHSD17B10 | |
| SCHEMBL25564685 | 0.76 | PDE4B (0.45) | PDE4B | |
| SCHEMBL27176094 | 0.74 | HPGD (0.49) | IDO1ALDH1A1USP2HPGDHSD17B10 | |
| SCHEMBL27176098 | 0.70 | CA12 (0.41) | IDO1ALDH1A1USP2HPGDHSD17B10 | |
| SCHEMBL27176100 | 0.70 | HSP90AA1 (0.51) | IDO1ALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL27176117 | 0.70 | SMN1; SMN2 (0.40) | IDO1ALDH1A1USP2HPGDHSD17B10 | |
| SCHEMBL27176091 | 0.68 | PDGFRB (0.39) | IDO1ALDH1A1USP2HPGDHSD17B10 | |
| SCHEMBL28954958 | 0.68 | IDO1 (0.63) | IDO1ALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL17498427 | 0.67 | CDK5 (0.40) | IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088233-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-25 | — | — | WO | disclosed |