SCHEMBL25565386

SCHEMBL25565386

Bc1c(-c2ccc(OC)c(F)c2C)ccc(OC)c1F

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.33
TUBB1 Q9H4B7 3/20 0.33
PTGS1 P23219 2/20 0.33
ACHE P22303 1/20 0.32
CYP17A1 P05093 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
GRM8 O00222 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
TACR1 P25103 1/20 0.32
GRM7 Q14831 1/20 0.32
P2RX7 Q99572 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25565391 0.91 TUBB1 (0.34) PTGS2TUBB1PTGS1CYP17A1CYP3A4
SCHEMBL16805986 0.76 KCNN4 (0.43) TUBB1CYP1A2KDM4EMEN1MAPT
SCHEMBL16805983 0.74 MAPT (0.41) PTGS2PTGS1CYP3A4CYP1A2CYP2C9
SCHEMBL16806006 0.74 ACHE (0.41) PTGS2PTGS1ACHECYP3A4KDM4E
SCHEMBL5352012 0.74 TUBB1 (0.40) PTGS2TUBB1ACHEGAAKMT2A
SCHEMBL16805991 0.73 MEN1 (0.45) PTGS2CYP3A4CYP1A2CYP2C9KDM4E
SCHEMBL25565393 0.72 SYK (0.30)
SCHEMBL8240850 0.71 TUBB1 (0.43) TUBB1ACHECYP3A4P2RX7KDM4E
SCHEMBL9847952 0.71 TUBB1 (0.43) TUBB1ACHECYP3A4CYP1A2CYP2C9
SCHEMBL15685342 0.71 HTR2A (0.41) PTGS2TUBB1CYP17A1CYP3A4CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159826-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING THE SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-05-25 US disclosed