SCHEMBL25565473

SCHEMBL25565473

c1ccc(-c2ccc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccc6c(c5)-c5ccccc5CC6)ccc43)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 1/20 0.41
SERPINE1 P05121 1/20 0.38
TSPO P30536 1/20 0.36
HDAC4 P56524 1/20 0.36
EDNRA P25101 2/20 0.34
EDNRB P24530 1/20 0.34
MAPT P10636 2/20 0.34
NPC1 O15118 1/20 0.34
PKM P14618 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B3 P37058 1/20 0.33
DNM1 Q05193 1/20 0.32
KMT2A Q03164 2/20 0.32
IL1R1 P14778 1/20 0.32
SRD5A1 P18405 1/20 0.31
SRD5A2 P31213 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27266442 0.96 L3MBTL1 (0.46) KDM4EL3MBTL1ATMSERPINE1TSPO
SCHEMBL17636993 0.93 KDM4E (0.41) KDM4EL3MBTL1ATMSERPINE1TSPO
SCHEMBL18830882 0.91 KDM4E (0.39) KDM4EL3MBTL1ATMSERPINE1TSPO
SCHEMBL17920273 0.90 SERPINE1 (0.34) KDM4EL3MBTL1ATMSERPINE1TSPO
SCHEMBL10207572 0.90 L3MBTL1 (0.45) KDM4EL3MBTL1ATMSERPINE1TSPO
SCHEMBL23468772 0.89 KDM4E (0.41) KDM4EL3MBTL1ATMSERPINE1TSPO
SCHEMBL23468748 0.89 KDM4E (0.41) KDM4EL3MBTL1ATMSERPINE1TSPO
SCHEMBL15258307 0.89 KDM4E (0.46) KDM4EL3MBTL1ATMTSPOHDAC4
SCHEMBL17636985 0.89 KDM4E (0.46) KDM4EL3MBTL1ATMTSPOHDAC4
SCHEMBL20097797 0.88 KDM4E (0.43) KDM4EL3MBTL1ATMTSPOHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186898-A1 COMPOSITION FOR ORGANIC ELECTRONIC COMPOUNDS Merck Patent GmbH (DE) 2023-05-31 EP disclosed