Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | ESR1 | P03372 | 2/20 | 0.64 |
| ▸ | ESRRG | P62508 | 2/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.64 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.63 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555750 | 0.86 | NPC1 (0.69) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL28185509 | 0.84 | NPC1 (0.76) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL23447715 | 0.83 | NPC1 (1.00) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL95403 | 0.83 | NPC1 (0.73) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL18941291 | 0.83 | NPC1 (0.73) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL4773188 | 0.82 | PTPN1 (0.69) | NPC1RAB9AMEN1KMT2ATRPV1 | |
| SCHEMBL387376 | 0.82 | TRPV1 (0.81) | NPC1RAB9AMEN1KMT2AKCNK3 | |
| SCHEMBL7301550 | 0.80 | KCNK9 (0.73) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL2358354 | 0.80 | MEN1 (1.00) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL29489337 | 0.79 | NPC1 (0.73) | NPC1RAB9AHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |