Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177468 | 0.93 | TRPV1 (0.81) | TRPV1PTPN1POLBMEN1KMT2A | |
| SCHEMBL1315526 | 0.86 | PTPN1 (0.87) | PTPN1HDAC2HDAC8HDAC6POLB | |
| SCHEMBL26286924 | 0.86 | PGR (0.74) | TRPV1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14715847 | 0.84 | PTPN1 (0.84) | PTPN1HDAC2HDAC8HDAC6POLB | |
| SCHEMBL15483230 | 0.84 | TRPV1 (0.69) | TRPV1POLBMEN1KMT2AKDM4E | |
| SCHEMBL3786940 | 0.84 | TRPV1 (0.59) | TRPV1PTPN1HDAC2HDAC8HDAC6 | |
| SCHEMBL2560174 | 0.82 | TRPV1 (0.67) | TRPV1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4773188 | 0.82 | PTPN1 (0.69) | TRPV1PTPN1POLBMEN1KMT2A | |
| SCHEMBL20480843 | 0.82 | RAB9A (0.76) | TRPV1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL28259723 | 0.82 | POLB (0.76) | TRPV1POLBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4157998-A1 | GEL FOR USE IN GASTROINTESTINAL ENDOSCOPY AND ENDODERMAL, EPIDERMAL, AND OTHER MUCOSAL USES | The Johns Hopkins University (US) | 2023-04-05 | — | — | EP | claimed |
| EP-3344232-B1 | MICELLES FOR MUCOADHESIVE DRUG DELIVERY | UNIV MCMASTER (CA) | 2022-01-26 | — | — | EP | claimed |
| US-10611908-B2 | Micelles for mucoadhesive drug delivery | MCMASTER UNIVERSITY (CA) | 2020-04-07 | — | — | US | claimed |
| US-20180265694-A1 | Micelles for Mucoadhesive Drug Delivery | MCMASTER UNIVERSITY (CA) | 2018-09-20 | — | — | US | claimed |
| EP-3344232-A1 | MICELLES FOR MUCOADHESIVE DRUG DELIVERY | Mcmaster University (CA) | 2018-07-11 | — | — | EP | claimed |
| WO-2017035656-A1 | MICELLES FOR MUCOADHESIVE DRUG DELIVERY | MCMASTER UNIVERSITY (CA) | 2017-03-09 | — | — | WO | claimed |
| US-12252474-B2 | Ultraviolet absorber having excellent heat resistance and long-wavelength absorption | MIYOSHI OIL & FAT CO., LTD. (JP) | 2025-03-18 | — | — | US | disclosed |
| CN-113728070-B | Ultraviolet absorber excellent in heat resistance and long-wavelength absorption | 三吉油脂株式会社 | 2024-03-08 | — | — | CN | disclosed |
| US-20230139250-A1 | FORMULATIONS OF TIE-2 ACTIVATORS AND METHODS OF USE THEREOF | EYEPOINT PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
| EP-4157998-A1 | GEL FOR USE IN GASTROINTESTINAL ENDOSCOPY AND ENDODERMAL, EPIDERMAL, AND OTHER MUCOSAL USES | The Johns Hopkins University (US) | 2023-04-05 | — | — | EP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11413242-B2 | Formulations of Tie-2 activators and methods of use thereof | EyePoint Pharmaceuticals, Inc. (US) | 2022-08-16 | — | — | US | disclosed |
| US-20220162174-A1 | ULTRAVIOLET ABSORBER HAVING EXCELLENT HEAT RESISTANCE AND LONG-WAVELENGTH ABSORPTION | MIYOSHI OIL & FAT CO., LTD. (JP) | 2022-05-26 | — | — | US | disclosed |
| US-6660744-B1 | Kinase inhibitors | ABBOTT GMBH & CO. KG (DE) | 2003-12-09 | — | — | US | disclosed |
| EP-1212327-B1 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | BASF AG (DE) | 2003-08-20 | — | — | EP | disclosed |
| US-20030044840-A1 | Preparation and uses of conjugated solid supports for boronic acids | GOVERNORS OF THE UNIVERSITY OF ALBERTA, THE (CA) | 2003-03-06 | — | — | US | disclosed |
| US-20020156081-A1 | Pyrazolopyrimidines as therapeutic agents | ABBOTT LABORATORIES (US) | 2002-10-24 | — | — | US | disclosed |
| WO-2002080926-A1 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | ABBOTT GMBH & CO. KG (DE) | 2002-10-17 | — | — | WO | disclosed |
| EP-1212327-A2 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001019829-A2 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11413242-B2 | Formulations of Tie-2 activators and methods of use thereof | TIE1, TEK, KDR | TRPV1 3331/4885PTPN1 1677/4885HDAC2 2475/4885 |
| US-20030044840-A1 | Preparation and uses of conjugated solid supports for boronic acids | SLC43A1, SBDS, SLC7A5 | TRPV1 4144/4885PTPN1 3751/4885HDAC2 3467/4885 |
| US-20220162174-A1 | ULTRAVIOLET ABSORBER HAVING EXCELLENT HEAT RESISTANCE AND LONG-WAVELENGTH ABSORPTION | HSPB1, HEATR1, TAS1R3 | TRPV1 38/4885PTPN1 4267/4885HDAC2 1979/4885 |
| US-12252474-B2 | Ultraviolet absorber having excellent heat resistance and long-wavelength absorption | HSPB1, HEATR1, TAS1R3 | TRPV1 38/4885PTPN1 4267/4885HDAC2 1979/4885 |
| US-20230139250-A1 | FORMULATIONS OF TIE-2 ACTIVATORS AND METHODS OF USE THEREOF | TIE1, TEK, KDR | TRPV1 3331/4885PTPN1 1677/4885HDAC2 2475/4885 |
| US-20020156081-A1 | Pyrazolopyrimidines as therapeutic agents | DPYD, CYP2D6, UGT1A1 | TRPV1 1987/4885PTPN1 765/4885HDAC2 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.