Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.59 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891085 | 0.85 | ACHE (0.67) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL22703779 | 0.81 | ACHE (0.61) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL1286687 | 0.80 | ACHE (0.78) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL81186 | 0.79 | — | — | |
| SCHEMBL24890773 | 0.79 | ACHE (0.59) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL23983253 | 0.79 | ACHE (0.59) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL23491277 | 0.78 | CHRM5 (0.54) | ACHEHRH3CHRM5ADRA2CSMN1; SMN2 | |
| SCHEMBL26461975 | 0.78 | ACHE (0.75) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL23492270 | 0.78 | ACHE (0.34) | ACHECHRM5ADRA2CSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL1492464 | 0.77 | ACHE (0.48) | ACHECARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |