Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | GBA1 | P04062 | 2/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | ARG2 | P78540 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24716276 | 0.90 | ACHE (0.54) | ACHEGBA1GNAO1CACNA2D1CACNA1B | |
| SCHEMBL19560910 | 0.89 | ACHE (0.43) | ACHEGBA1GNAO1CARM1PRMT6 | |
| SCHEMBL13661316 | 0.89 | ACHE (0.43) | ACHEGBA1GNAO1CHRM5ADRA2C | |
| SCHEMBL25477588 | 0.89 | ACHE (0.43) | ACHEGBA1GNAO1CARM1PRMT6 | |
| SCHEMBL13661595 | 0.88 | ACHE (0.64) | ACHEGBA1GNAO1CACNA2D1CACNA1B | |
| Hydrochloric Acid SCHEMBL22033207 | 0.86 | ACHE (0.62) | ACHEGBA1GNAO1CACNA2D1CACNA1B | |
| SCHEMBL21946274 | 0.86 | GBA1 (0.56) | ACHEGBA1GNAO1CACNA2D1CACNA1B | |
| SCHEMBL10130156 | 0.86 | ACHE (0.59) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL10130194 | 0.86 | ACHE (0.59) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL478539 | 0.86 | ACHE (0.59) | ACHECARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |