Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 15/20 | 0.82 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.82 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.80 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727163 | 0.90 | ADORA3 (1.00) | ADORA3ADORA1TMIGD3HSP90B1 | |
| SCHEMBL16774258 | 0.89 | ADORA3 (1.00) | ADORA3ADORA1TMIGD3ADORA2A | |
| SCHEMBL16774370 | 0.89 | ADORA3 (1.00) | ADORA3ADORA1TMIGD3ADORA2A | |
| SCHEMBL25566749 | 0.86 | ADORA3 (0.82) | ADORA3ADORA1TMIGD3ADORA2A | |
| SCHEMBL25566683 | 0.84 | ADORA3 (1.00) | ADORA3ADORA1TMIGD3ADORA2A | |
| SCHEMBL16774384 | 0.84 | ADORA3 (1.00) | ADORA3ADORA1TMIGD3ADORA2A | |
| SCHEMBL29573481 | 0.81 | ADORA3 (0.70) | ADORA3ADORA1TMIGD3HSP90B1ADORA2A | |
| SCHEMBL29574049 | 0.81 | ADORA3 (0.72) | ADORA3ADORA1TMIGD3HSP90B1 | |
| SCHEMBL16774293 | 0.81 | ADORA3 (0.85) | ADORA3ADORA1TMIGD3 | |
| SCHEMBL19799159 | 0.81 | HSP90B1 (0.80) | ADORA3ADORA1TMIGD3HSP90B1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091791-A1 | METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |