Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.60 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24832984 | 0.84 | DDB1 (0.72) | DDB1CRBNPOLB | |
| SCHEMBL30735101 | 0.84 | DDB1 (0.72) | DDB1CRBN | |
| SCHEMBL30663037 | 0.79 | CRBN (0.56) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL31434024 | 0.79 | DDB1 (0.59) | DDB1CRBNPOLB | |
| Hydrochloric Acid SCHEMBL31433949 | 0.79 | DDB1 (0.59) | DDB1CRBNPOLB | |
| Hydrochloric Acid SCHEMBL31434041 | 0.79 | CRBN (0.55) | DDB1CRBN | |
| SCHEMBL31433539 | 0.78 | DDB1 (0.50) | DDB1CRBNPOLB | |
| SCHEMBL31433558 | 0.78 | DDB1 (0.50) | DDB1CRBNPOLB | |
| SCHEMBL31575007 | 0.76 | DDB1 (0.73) | DDB1CRBN | |
| SCHEMBL25027088 | 0.76 | DDB1 (0.77) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |