Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24524131 | 0.81 | MEN1 (0.67) | MEN1KMT2AGAAKDM4EESR2 | |
| SCHEMBL25566978 | 0.80 | KMT2A (0.41) | MEN1KMT2AGAAKDM4EESR2 | |
| SCHEMBL25567245 | 0.78 | MEN1 (0.43) | MEN1KMT2AGAAKDM4EESR2 | |
| SCHEMBL25567084 | 0.73 | MEN1 (0.37) | MEN1KMT2AGAAKDM4ETSHR | |
| SCHEMBL12290803 | 0.72 | KDM4E (0.39) | KDM4EESR2TSHRCHRNB2CHRNA4 | |
| SCHEMBL25569548 | 0.71 | CYP11B2 (0.38) | ESR2KDM1ACA1CA2 | |
| SCHEMBL25567146 | 0.71 | MEN1 (0.56) | MEN1KMT2AGAAKDM4ETSHR | |
| SCHEMBL3032522 | 0.70 | CXCR2 (0.47) | MEN1KMT2AGAAKDM4EESR2 | |
| SCHEMBL25567067 | 0.69 | DYRK1A (0.33) | — | |
| SCHEMBL29508732 | 0.68 | MEN1 (1.00) | MEN1KMT2AGAAKDM4ESNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094412-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-06-01 | — | — | WO | disclosed |