Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.48 |
| ▸ | FPR2 | P25090 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885375 | 0.87 | CRBN (0.52) | NAMPTPTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL16047746 | 0.81 | CRBN (0.58) | NAMPTPTPN2PTPN1PTPN6CRBN | |
| SCHEMBL30847573 | 0.81 | CRBN (0.58) | NAMPTPTPN2PTPN1PTPN6CRBN | |
| SCHEMBL7667693 | 0.79 | NAMPT (0.69) | NAMPTPTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL16835041 | 0.78 | NAMPT (0.67) | NAMPTPTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL5466754 | 0.77 | NAMPT (0.61) | NAMPTPTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL10127488 | 0.76 | NAMPT (0.71) | NAMPTPTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL15587463 | 0.76 | NAMPT (0.65) | NAMPTPTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL15379413 | 0.75 | PTPN2 (0.67) | NAMPTPTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL3654523 | 0.75 | BRD4 (0.48) | CRBNCA12CA1CA9TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |