Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 6/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154463 | 0.86 | HDAC3 (0.45) | HDAC3ANPEPSMYD3CRBN | |
| SCHEMBL154464 | 0.86 | HDAC3 (0.45) | HDAC3ANPEPSMYD3CRBN | |
| SCHEMBL152807 | 0.82 | HDAC3 (0.45) | HDAC3SMYD3CRBN | |
| SCHEMBL155059 | 0.81 | HDAC3 (0.41) | HDAC3ANPEPSMYD3CRBN | |
| SCHEMBL155927 | 0.79 | HDAC3 (0.44) | HDAC3SMYD3CRBNKMT2A | |
| SCHEMBL155351 | 0.78 | HDAC3 (0.42) | HDAC3PARP1SMYD3CRBN | |
| SCHEMBL25565793 | 0.77 | HDAC3 (0.38) | HDAC3PARP1ANPEPSMYD3CRBN | |
| SCHEMBL154844 | 0.77 | SMN1; SMN2 (0.42) | HDAC3PARP1SMYD3CRBNKMT2A | |
| SCHEMBL13449528 | 0.76 | HDAC3 (0.43) | HDAC3ANPEPSMYD3CRBN | |
| SCHEMBL3660566 | 0.76 | SMYD3 (0.54) | HDAC3SMYD3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |