Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 10/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155351 | 0.78 | HDAC3 (0.42) | HDAC3SMYD3CRBNPARP1HDAC1 | |
| SCHEMBL152807 | 0.78 | HDAC3 (0.45) | HDAC3SMYD3CRBNHDAC1 | |
| SCHEMBL25567414 | 0.77 | HDAC3 (0.41) | HDAC3SMYD3CRBNPARP1ANPEP | |
| SCHEMBL155927 | 0.76 | HDAC3 (0.44) | HDAC3SMYD3CRBNHDAC1GRIN1 | |
| SCHEMBL154463 | 0.76 | HDAC3 (0.45) | HDAC3SMYD3CRBNANPEPHDAC1 | |
| SCHEMBL154464 | 0.76 | HDAC3 (0.45) | HDAC3SMYD3CRBNANPEPHDAC1 | |
| SCHEMBL154844 | 0.75 | SMN1; SMN2 (0.42) | HDAC3SMYD3CRBNPARP1HDAC1 | |
| SCHEMBL25565806 | 0.74 | RAB9A (0.58) | EPHX2 | |
| SCHEMBL159194 | 0.74 | HDAC3 (0.39) | HDAC3SMYD3CRBNHDAC1EPHX2 | |
| SCHEMBL25567411 | 0.73 | ALDH1A1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |