SCHEMBL25567434 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	CRBN	Q96SW2	19/20	0.60

▸	DDB1	Q16531	16/20	0.60

▸	IKZF3	Q9UKT9	2/20	0.39

▸	ALDH1A1	P00352	1/20	0.39

▸	CHRM2	P08172	1/20	0.39

▸	OPRM1	P35372	1/20	0.39

▸	CYP1A2	P05177	1/20	0.39

▸	TSHR	P16473	1/20	0.39

▸	TDP1	Q9NUW8	1/20	0.39

▸	TNF	P01375	2/20	0.39

▸	IL1B	P01584	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25595698	0.88	CRBN (0.60)	CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL24207099	0.87	CRBN (0.59)	CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL25595695	0.86	CRBN (0.60)	CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL24673697	0.86	CRBN (0.60)	CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL23572071	0.85	CRBN (0.57)	CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL25567437	0.85	CRBN (0.56)	CRBNDDB1TNF
SCHEMBL25834828	0.85	CRBN (0.59)	CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL25338647	0.83	CRBN (0.55)	CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL29751415	0.82	CRBN (0.54)	CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL24207707	0.82	CRBN (0.54)	CRBNDDB1IKZF3ALDH1A1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023083194-A1	WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF	杭州格博生物医药有限公司	2023-05-19	—	—	WO	disclosed