Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 14/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23744349 | 0.85 | CRBN (0.53) | CRBNDDB1TNF | |
| SCHEMBL25567434 | 0.85 | CRBN (0.60) | CRBNDDB1TNF | |
| SCHEMBL32672217 | 0.83 | CRBN (0.53) | CRBNDDB1TNF | |
| SCHEMBL32672253 | 0.82 | CRBN (0.52) | CRBNDDB1TNF | |
| SCHEMBL24480227 | 0.81 | CRBN (0.62) | CRBNDDB1TNF | |
| SCHEMBL25595695 | 0.80 | CRBN (0.60) | CRBNDDB1TNF | |
| SCHEMBL23744890 | 0.80 | CRBN (0.51) | CRBNDDB1TNF | |
| SCHEMBL24607355 | 0.79 | CRBN (0.56) | CRBNDDB1TNF | |
| SCHEMBL29751098 | 0.79 | CRBN (0.56) | CRBNDDB1TNF | |
| SCHEMBL24204750 | 0.78 | CRBN (0.55) | CRBNDDB1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |