Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 4/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.52 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330035 | 0.89 | GRN (0.48) | GRNSORT1SMYD3AKR1C3L3MBTL1 | |
| SCHEMBL15330267 | 0.84 | GRN (0.53) | GRNSORT1SMYD3AKR1C3L3MBTL1 | |
| SCHEMBL2562476 | 0.83 | SMYD3 (0.47) | GRNSORT1SMYD3AKR1C3L3MBTL1 | |
| SCHEMBL15332560 | 0.76 | SMYD3 (0.47) | SMYD3AKR1C3L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL29955250 | 0.75 | SMYD3 (0.47) | GRNSORT1SMYD3AKR1C3L3MBTL1 | |
| SCHEMBL15332548 | 0.75 | SMYD3 (0.46) | GRNSORT1SMYD3AKR1C3L3MBTL1 | |
| SCHEMBL2562433 | 0.75 | SMYD3 (0.46) | GRNSORT1SMYD3AKR1C3L3MBTL1 | |
| SCHEMBL29953517 | 0.75 | CA2 (0.47) | SMYD3AKR1C3L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL15332731 | 0.75 | CA2 (0.47) | SMYD3AKR1C3L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL15332388 | 0.72 | GRN (0.38) | GRNSORT1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |