Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 8/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330016 | 0.86 | SYK (0.41) | SYKCNR2CNR1MMP1MMP13 | |
| SCHEMBL2561533 | 0.82 | NPC1 (0.41) | SYKCNR2CNR1BACE1ENPP2 | |
| SCHEMBL13724339 | 0.74 | SYK (0.51) | SYKCNR2CNR1BACE1CYP2C8 | |
| SCHEMBL2553075 | 0.71 | NPC1 (0.42) | — | |
| SCHEMBL13723608 | 0.70 | SYK (0.47) | SYKCNR2CNR1BACE1CYP2C8 | |
| SCHEMBL3548134 | 0.70 | SYK (0.47) | SYKCNR2CNR1BACE1CYP2C8 | |
| SCHEMBL2560178 | 0.70 | ALDH1A3 (0.54) | SYKCNR2CNR1MMP1MMP13 | |
| SCHEMBL15331610 | 0.69 | POLB (0.48) | SYKCNR2CNR1MMP1MMP13 | |
| SCHEMBL17774943 | 0.68 | SYK (0.48) | SYKCNR2CNR1BACE1CYP2C8 | |
| SCHEMBL2558897 | 0.68 | NPC1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |