Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | FLT3 | P36888 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16026822 | 0.86 | EGFR (0.57) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9891521 | 0.85 | EGFR (0.64) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25567678 | 0.84 | EGFR (0.56) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL1464298 | 0.83 | EGFR (0.62) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL12102149 | 0.83 | EGFR (0.62) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL1758718 | 0.83 | EGFR (0.66) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL14960393 | 0.82 | EGFR (0.60) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL2951112 | 0.81 | RAB9A (0.77) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL12376186 | 0.81 | EGFR (0.59) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4112548 | 0.80 | EGFR (0.66) | EGFRNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |