Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329856 | 1.00 | CNR1 (0.42) | CNR1CNR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25567708 | 0.73 | SMN1; SMN2 (0.47) | CNR1CNR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25567711 | 0.72 | SMN1; SMN2 (0.44) | CNR1CNR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25255613 | 0.69 | SMN1; SMN2 (0.44) | CNR1CNR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30415447 | 0.67 | CNR2 (0.66) | CNR1CNR2SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL16122909 | 0.67 | CNR2 (0.66) | CNR1CNR2SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL23881422 | 0.66 | KDM1A (0.44) | SMN1; SMN2HTTALDH1A1MAPTKDM4E | |
| SCHEMBL16718897 | 0.66 | CNR1 (0.45) | CNR1CNR2MEN1KMT2AALDH1A1 | |
| SCHEMBL30592410 | 0.66 | CNR2 (0.48) | CNR1CNR2SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL26110001 | 0.66 | CNR2 (0.48) | CNR1CNR2SMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023101895-A1 | FUSED PYRAZOLE UREA ANALOGS AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2023-06-08 | — | — | WO | disclosed |