SCHEMBL25567903

SCHEMBL25567903

Clc1cccc2c1oc1cc(-c3ccccc3-c3cccc4oc5ccccc5c34)ccc12

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.48
AHR P35869 6/20 0.44
PRKDC P78527 1/20 0.43
TTR P02766 4/20 0.39
BACE1 P56817 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 1/20 0.37
GGPS1 O95749 1/20 0.37
PIM1 P11309 1/20 0.35
CSNK2A2 P19784 1/20 0.35
CSNK2B P67870 1/20 0.35
PIM3 Q86V86 1/20 0.35
PIM2 Q9P1W9 1/20 0.35
PTGES2 Q9H7Z7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25567802 0.89 AHR (0.45) ALOX5AHRPRKDCTTRBACE1
SCHEMBL22129987 0.86 AHR (0.54) ALOX5AHRPRKDCTTRKDM4E
SCHEMBL26195566 0.85 AHR (0.64) ALOX5AHRPRKDCKDM4EMEN1
SCHEMBL25567907 0.85 ALOX5 (0.54) ALOX5AHRPRKDCTTRKDM4E
SCHEMBL25567683 0.85 ALOX5 (0.47) ALOX5AHRPRKDCTTRGGPS1
SCHEMBL23203691 0.83 ALOX5 (0.40) ALOX5AHRPRKDCTTRBACE1
SCHEMBL27334986 0.83 AHR (0.56) ALOX5AHRTTRBACE1KDM4E
SCHEMBL18820368 0.83 ALOX5 (0.56) ALOX5AHRPRKDCKDM4EMEN1
SCHEMBL23820547 0.83 AHR (0.40) ALOX5AHRPRKDCTTRBACE1
SCHEMBL24929445 0.81 ALOX5 (0.47) ALOX5AHRPRKDCTTRBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096209-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2023-06-01 WO disclosed