SCHEMBL25568592

SCHEMBL25568592

CC(C)C(=O)c1ccnn1CCC(O)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.36
FLT1 P17948 9/20 0.36
KDR P35968 9/20 0.36
PIK3CD O00329 1/20 0.34
CNR2 P34972 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ATM Q13315 1/20 0.31
CBLB Q13191 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25862645 0.91 FLT1 (0.35) MAPK1FLT1KDRPIK3CDCNR2
SCHEMBL22125947 0.85 FLT1 (0.38) MAPK1FLT1KDRCNR2
SCHEMBL31582206 0.85 FLT1 (0.38) MAPK1FLT1KDRCNR2
SCHEMBL31582304 0.85 FLT1 (0.38) MAPK1FLT1KDRCNR2
SCHEMBL25854009 0.84 FLT1 (0.36) MAPK1FLT1KDRCNR2NPC1
SCHEMBL22125614 0.83 FLT1 (0.37) MAPK1FLT1KDRCNR2
SCHEMBL17452633 0.83 MAPK1 (0.40) MAPK1FLT1KDRPIK3CDCNR2
SCHEMBL25564515 0.82 MAPK1 (0.35) MAPK1FLT1KDRCNR2NPC1
SCHEMBL24103836 0.81 KDM4E (0.40) FLT1KDRNPC1RAB9AALDH1A1
SCHEMBL22143733 0.80 MAPK1 (0.49) MAPK1CNR2CBLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159465-A1 IMMUNOMODULATOR HITGEN INC. (CN) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159465-A1 IMMUNOMODULATOR IL2, IL17A, IL2RA MAPK1 2714/4885FLT1 2561/4885KDR 3968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.