SCHEMBL25854009

SCHEMBL25854009

CC(C)(C)C(=O)c1ccnn1CCC(O)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 10/20 0.36
KDR P35968 10/20 0.36
CNR2 P34972 1/20 0.34
MAPK1 P28482 1/20 0.33
KMT2A Q03164 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25568591 0.86 FLT1 (0.38) FLT1KDRMAPK1KMT2AL3MBTL1
SCHEMBL22125947 0.85 FLT1 (0.38) FLT1KDRCNR2MAPK1
SCHEMBL31582206 0.85 FLT1 (0.38) FLT1KDRCNR2MAPK1
SCHEMBL31582304 0.85 FLT1 (0.38) FLT1KDRCNR2MAPK1
SCHEMBL25562724 0.84 CNR2 (0.34) FLT1KDRCNR2
SCHEMBL25568592 0.84 MAPK1 (0.36) FLT1KDRCNR2MAPK1KMT2A
SCHEMBL22125614 0.83 FLT1 (0.37) FLT1KDRCNR2MAPK1
SCHEMBL25862645 0.83 FLT1 (0.35) FLT1KDRCNR2MAPK1KMT2A
SCHEMBL25564515 0.82 MAPK1 (0.35) FLT1KDRCNR2MAPK1KMT2A
SCHEMBL25564501 0.81 FLT1 (0.39) FLT1KDRCNR2MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227437-A1 IMMUNOMODULATOR HITGEN INC (CN) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227437-A1 IMMUNOMODULATOR IL17A, IL2, IL2RA FLT1 3452/4885KDR 4480/4885CNR2 1393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.