SCHEMBL2556864

SCHEMBL2556864

CC(=O)c1cc(CC(O)C(=O)O)ccc1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.68
ALOX15 P16050 5/20 0.49
KDM4E B2RXH2 3/20 0.49
RECQL P46063 3/20 0.49
HIF1A Q16665 3/20 0.49
HSD17B10 Q99714 3/20 0.49
LCK P06239 2/20 0.49
SLC7A5 Q01650 2/20 0.49
USP2 O75604 2/20 0.49
ADORA3 P0DMS8 2/20 0.49
HTR2A P28223 2/20 0.49
PTGS2 P35354 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
EGFR P00533 1/20 0.49
FYN P06241 1/20 0.49
PTGS1 P23219 1/20 0.49
KLKB1 P03952 1/20 0.46
CTSB P07858 1/20 0.46
MMP9 P14780 1/20 0.46
DNMT1 P26358 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2556861 1.00 KDM6B (0.68) KDM6BALOX15KDM4ERECQLHIF1A
SCHEMBL2558959 0.84 SLC7A5 (0.71) KDM6BALOX15KDM4ERECQLHIF1A
SCHEMBL2554990 0.84 SLC7A5 (0.71) KDM6BALOX15KDM4ERECQLHIF1A
SCHEMBL2558965 0.84 SLC7A5 (0.71) KDM6BALOX15KDM4ERECQLHIF1A
SCHEMBL30665436 0.84 SLC7A5 (0.71) KDM6BALOX15KDM4ERECQLHIF1A
SCHEMBL14032222 0.84 ALOX15 (0.49) KDM6BALOX15KDM4ERECQLHIF1A
Hydrochloric Acid SCHEMBL6758817 0.83 SLC7A5 (0.69) ALOX15KDM4ERECQLHIF1AHSD17B10
Hydrochloric Acid SCHEMBL21519811 0.83 SLC7A5 (0.69) ALOX15KDM4ERECQLHIF1AHSD17B10
SCHEMBL18469325 0.81 KDM6B (1.00) KDM6BALOX15KDM4ERECQLHIF1A
SCHEMBL5691448 0.81 KDM6B (1.00) KDM6BALOX15KDM4ERECQLHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed
CN-102153462-A Method for synthesizing tanshinol UNIV JINAN 2011-08-17 CN disclosed