Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.41 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17135791 | 0.79 | AKT2 (0.41) | AKT2AKT1MAPK8AURKAAURKB | |
| SCHEMBL25693365 | 0.75 | MAPK8 (0.48) | AKT2AKT1MAPK8AURKAAURKB | |
| SCHEMBL3419294 | 0.74 | AKT2 (0.52) | AKT2AKT1MAPK8AURKAAURKB | |
| SCHEMBL27754726 | 0.73 | HSP90AA1 (0.42) | MKNK1MKNK2IRAK4SCN9A | |
| SCHEMBL19015307 | 0.72 | MAPK8 (0.40) | AKT2AKT1MAPK8AURKAAURKB | |
| SCHEMBL30462066 | 0.72 | HSP90AA1 (0.40) | MAPK1IRAK4 | |
| SCHEMBL31213013 | 0.71 | MAPK8 (0.55) | AKT2AKT1MAPK8AURKAAURKB | |
| SCHEMBL19750666 | 0.71 | MAPK8 (0.55) | AKT2AKT1MAPK8AURKAAURKB | |
| SCHEMBL1018167 | 0.71 | NPC1 (0.47) | MAPK1SCN9A | |
| SCHEMBL12443811 | 0.71 | MEN1 (0.48) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250345329-A1 | HETEROARYL DERIVATIVE COMPOUND AND USES THEREOF | VORONOI INC (KR) | 2025-11-13 | — | — | US | disclosed |
| EP-4534532-A1 | HETEROARYL DERIVATIVE COMPOUND AND USES THEREOF | Voronoi Inc. (KR) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023174406-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-09-21 | — | — | WO | disclosed |
| EP-2558468-A1 | 5, 7-SUBSTITUTED-IMIDAZO [1, 2-C]PYRIMIDINES AS INHIBITORS OF JAK KINASES | Array Biopharma, Inc. (US) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011130146-A1 | 5, 7-SUBSTITUTED-IMIDAZO [1, 2-C] PYRIMIDINES AS INHIBITORS OF JAK KINASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250345329-A1 | HETEROARYL DERIVATIVE COMPOUND AND USES THEREOF | EGFR, ERBB2, ERBB3 | AKT2 94/4885AKT1 73/4885MAPK8 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.