Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | VCP | P55072 | 3/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 6/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953758 | 0.94 | RAD52 (0.52) | RAD52VCPCARM1PRMT6MEN1 | |
| SCHEMBL24204306 | 0.90 | ACE2 (0.44) | RAD52VCPCARM1PRMT6MEN1 | |
| SCHEMBL3605906 | 0.90 | RAD52 (0.53) | RAD52VCPCARM1PRMT6MEN1 | |
| SCHEMBL21549043 | 0.88 | RAD52 (0.66) | RAD52VCPCARM1PRMT6KMT2A | |
| Hydrochloric Acid SCHEMBL3598388 | 0.88 | RAD52 (0.51) | RAD52VCPCARM1PRMT6MEN1 | |
| SCHEMBL24204664 | 0.87 | MEN1 (0.47) | RAD52CARM1PRMT6MEN1KMT2A | |
| SCHEMBL24351559 | 0.82 | ACE2 (0.36) | RAD52VCPCARM1PRMT6MEN1 | |
| SCHEMBL24802106 | 0.81 | ACE2 (0.39) | RAD52VCPCARM1PRMT6MEN1 | |
| SCHEMBL24922070 | 0.80 | CARM1 (0.40) | RAD52CARM1PRMT6MEN1KMT2A | |
| SCHEMBL24352365 | 0.79 | RAD52 (0.39) | RAD52VCPCARM1PRMT6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |