Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PPID | Q08752 | 1/20 | 0.32 |
| ▸ | PPIG | Q13427 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26378171 | 0.92 | LMNA (0.37) | ALDH1A1KDM4EHDAC4GRIN2DGRIN3B | |
| SCHEMBL25569243 | 0.88 | SLC18A3 (0.35) | ALDH1A1KDM4ESLC18A3PRKCAMEN1 | |
| SCHEMBL25569238 | 0.88 | SLC18A3 (0.35) | ALDH1A1KDM4ESLC18A3PRKCAMEN1 | |
| SCHEMBL26378117 | 0.84 | PTPN1 (0.39) | HDAC4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL26378231 | 0.84 | PTPN1 (0.39) | HDAC4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16142101 | 0.84 | HDAC4 (0.38) | POLBHDAC4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL16139860 | 0.82 | KDM4E (0.42) | ALDH1A1KDM4EPOLBLMNAMEN1 | |
| SCHEMBL26378110 | 0.80 | HDAC4 (0.32) | POLBHDAC4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL26378109 | 0.80 | HDAC4 (0.32) | POLBHDAC4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL16139854 | 0.80 | HDAC4 (0.35) | POLBHDAC4GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4186889-A1 | LONG-ACTING AND LOW-ADDICTION COMPOUND AND PREPARATION METHOD THEREFOR | Shenzen Ruijian Biotechnology Co., Ltd. (CN) | 2023-05-31 | — | — | EP | disclosed |