SCHEMBL25569683

SCHEMBL25569683

Clc1nccc2sc3ccc4ccccc4c3c12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.51
MAPK1 P28482 2/20 0.51
LMNA P02545 1/20 0.51
MAPT P10636 1/20 0.51
APEX1 P27695 1/20 0.51
PMP22 Q01453 1/20 0.51
CYP2A6 P11509 4/20 0.37
PLAU P00749 2/20 0.37
F12 P00748 1/20 0.37
NCF1 P14598 1/20 0.37
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
NOS2 P35228 1/20 0.37
BACE1 P56817 1/20 0.37
NQO1 P15559 1/20 0.35
NQO2 P16083 1/20 0.35
HIPK2 Q9H2X6 1/20 0.35
ALDH1A1 P00352 2/20 0.34
TSHR P16473 2/20 0.34
HSD17B10 Q99714 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25569972 0.83 CYP3A4 (0.54) CYP3A4MAPK1LMNAMAPTAPEX1
SCHEMBL25672111 0.83 CYP3A4 (0.54) CYP3A4MAPK1LMNAMAPTAPEX1
SCHEMBL30062535 0.80 HSD17B10 (0.52) CYP3A4MAPK1CYP2A6NQO1NQO2
SCHEMBL13250616 0.80 HSD17B10 (0.52) CYP3A4MAPK1CYP2A6NQO1NQO2
SCHEMBL24057785 0.80 GPR3 (0.46) CYP3A4MAPK1LMNAMAPTAPEX1
SCHEMBL28838096 0.79 CYP3A4 (0.61) CYP3A4MAPK1LMNAMAPTAPEX1
SCHEMBL29836842 0.79 CYP3A4 (0.61) CYP3A4MAPK1LMNAMAPTAPEX1
SCHEMBL23972147 0.78 KDM4E (0.47) CYP3A4MAPK1LMNAMAPTAPEX1
SCHEMBL25547960 0.77 MAPT (0.40) CYP3A4MAPK1LMNAMAPTAPEX1
SCHEMBL24758926 0.75 CYP2A6 (0.50) MAPK1LMNACYP2A6NQO1NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096459-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-06-01 WO disclosed