⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24932465 | 0.79 | GRM5 (0.31) | — | |
| SCHEMBL24444263 | 0.76 | MEN1 (0.31) | — | |
| SCHEMBL25514500 | 0.74 | ATM (0.38) | — | |
| SCHEMBL22030758 | 0.70 | CYP2C19 (0.35) | — | |
| SCHEMBL22031248 | 0.68 | PIK3CD (0.41) | — | |
| SCHEMBL20009059 | 0.68 | GRM5 (0.35) | — | |
| SCHEMBL12293732 | 0.67 | GRM5 (0.36) | — | |
| SCHEMBL20069654 | 0.66 | LMNA (0.33) | — | |
| SCHEMBL3496579 | 0.66 | MEN1 (0.38) | — | |
| SCHEMBL22812179 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086400-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |