Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.82 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.82 |
| ▸ | EED | O75530 | 2/20 | 0.82 |
| ▸ | LMNA | P02545 | 2/20 | 0.82 |
| ▸ | GAA | P10253 | 2/20 | 0.82 |
| ▸ | TACR2 | P21452 | 2/20 | 0.82 |
| ▸ | TACR1 | P25103 | 2/20 | 0.82 |
| ▸ | HRH1 | P35367 | 2/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.82 |
| ▸ | MLNR | O43193 | 1/20 | 0.82 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.82 |
| ▸ | USP2 | O75604 | 1/20 | 0.82 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.82 |
| ▸ | EGFR | P00533 | 1/20 | 0.82 |
| ▸ | HLA-A | P04439 | 1/20 | 0.82 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.82 |
| ▸ | TP53 | P04637 | 1/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.82 |
| ▸ | LCK | P06239 | 1/20 | 0.82 |
| ▸ | FYN | P06241 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12045363 | 0.91 | KCNH2 (0.88) | KCNH2SSTR5EEDLMNAGAA | |
| Astemizole SCHEMBL4385 | 0.91 | KCNH2 (1.00) | KCNH2SSTR5EEDLMNAGAA | |
| SCHEMBL23696975 | 0.90 | KCNH2 (0.85) | KCNH2SSTR5EEDLMNAGAA | |
| Water SCHEMBL11485995 | 0.89 | KCNH2 (0.84) | KCNH2SSTR5EEDLMNAGAA | |
| SCHEMBL23696973 | 0.89 | KCNH2 (0.84) | KCNH2SSTR5EEDLMNAGAA | |
| SCHEMBL20715315 | 0.88 | KCNH2 (0.87) | KCNH2SSTR5EEDLMNAGAA | |
| Astemizole SCHEMBL1682436 | 0.87 | KCNH2 (0.92) | KCNH2SSTR5EEDLMNAGAA | |
| SCHEMBL9629272 | 0.86 | EED (1.00) | KCNH2SSTR5EEDLMNAGAA | |
| Astemizole SCHEMBL8026633 | 0.86 | KCNH2 (0.90) | KCNH2SSTR5EEDLMNAGAA | |
| SCHEMBL23696974 | 0.85 | KCNH2 (0.90) | KCNH2SSTR5EEDLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667666-B2 | Methods and compositions for treatment of cancer | CFD RESEARCH CORPORATION (US) | 2023-06-06 | — | — | US | disclosed |
| US-11667666-B2 | Methods and compositions for treatment of cancer | CFD RESEARCH CORPORATION (US) | 2023-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667666-B2 | Methods and compositions for treatment of cancer | TEK, VHL, TIE1 | KCNH2 4843/4885SSTR5 1626/4885EED 2194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.