SCHEMBL25572001

SCHEMBL25572001

CC(C)(C)OC(=O)N1CCN(C[C@@H]2CCNC2)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.43
DDB1 Q16531 1/20 0.42
CRBN Q96SW2 1/20 0.42
HPGD P15428 1/20 0.42
USP2 O75604 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.40
CACNA2D1 P54289 1/20 0.40
CACNA1B Q00975 1/20 0.40
CACNB1 Q02641 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40
RECQL P46063 1/20 0.40
NPC1 O15118 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30706198 1.00 CNR1 (0.43) CNR1DDB1CRBNHPGDUSP2
SCHEMBL5240935 1.00 CNR1 (0.43) CNR1DDB1CRBNHPGDUSP2
SCHEMBL25572000 1.00 CNR1 (0.43) CNR1DDB1CRBNHPGDUSP2
SCHEMBL2386299 0.92 CACNA2D1 (0.47) CNR1DDB1CRBNHPGDUSP2
SCHEMBL27307597 0.89 CACNA2D1 (0.45) CNR1DDB1CRBNHPGDUSP2
SCHEMBL20046121 0.89 USP2 (0.45) CNR1DDB1CRBNHPGDUSP2
SCHEMBL26924760 0.87 HPGD (0.46) CNR1DDB1CRBNHPGDUSP2
SCHEMBL19853552 0.86 CNR1 (0.41) CNR1DDB1CRBNHPGDUSP2
SCHEMBL29132260 0.85 NR1H2 (0.47) CNR1DDB1CRBNHPGDUSP2
Trifluoroacetic Acid SCHEMBL27848432 0.85 CACNA2D1 (0.45) CNR1DDB1CRBNHPGDUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270191-A1 QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. 2025-08-28 US disclosed
EP-4536649-A1 QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2025-04-16 EP disclosed
US-20240383877-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF UBIX THERAPEUTICS, INC. (KR) 2024-11-21 US disclosed
US-12122763-B2 Substituted piperidines for androgen receptor degradation UBIX THERAPEUTICS, INC. (KR) 2024-10-22 US disclosed
WO-2023244918-A1 QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2023-12-21 WO disclosed
US-20230348427-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF UBIX THERAPEUTICS, INC. (KR) 2023-11-02 US disclosed
US-20230348427-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF UBIX THERAPEUTICS, INC. (KR) 2023-11-02 US disclosed
EP-4186904-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF Ubix Therapeutics, Inc. (KR) 2023-05-31 EP disclosed
EP-4186904-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF Ubix Therapeutics, Inc. (KR) 2023-05-31 EP disclosed
CN-116157390-A Compounds for androgen receptor degradation and pharmaceutical uses thereof 尤比克斯治疗公司 2023-05-23 CN disclosed
WO-2022019597-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF 주식회사 유빅스테라퓨틱스 2022-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348427-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF AR, NR5A1, SHBG CNR1 483/4885DDB1 3709/4885CRBN 1967/4885
US-20250270191-A1 QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS BCL6, BCL6B, BCOR CNR1 3558/4885DDB1 141/4885CRBN 756/4885
US-20240383877-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF AR, NR5A1, ESRRA CNR1 205/4885DDB1 4456/4885CRBN 3222/4885
US-12122763-B2 Substituted piperidines for androgen receptor degradation AR, NR5A1, ESRRA CNR1 146/4885DDB1 4042/4885CRBN 1863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.