SCHEMBL2557248

SCHEMBL2557248

CC(=O)NCC(=O)N1CCCC1C=O

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 14/20 0.61
▸ PREP P48147 8/20 0.61
▸ FAP Q12884 7/20 0.61
▸ ALDH1A1 P00352 1/20 0.39
▸ DPP8 Q6V1X1 1/20 0.38
▸ DPP9 Q86TI2 1/20 0.38
▸ DPP7 Q9UHL4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2557245 1.00 DPP4 (0.61) DPP4PREPFAPALDH1A1DPP8
SCHEMBL18457433 0.89 DPP4 (0.60) DPP4PREPFAPALDH1A1DPP8
SCHEMBL8253564 0.84 DPP4 (0.44) DPP4PREPFAPDPP8DPP9
SCHEMBL8251922 0.83 DPP4 (0.57) DPP4PREPFAPDPP7
SCHEMBL8251925 0.80 DPP4 (0.44) DPP4PREPFAPDPP8DPP9
SCHEMBL8247017 0.80 MEN1 (0.49) DPP4PREPFAPALDH1A1DPP8
SCHEMBL20174118 0.78 DPP4 (0.58) DPP4PREPFAPDPP7
SCHEMBL8253605 0.78 DPP4 (0.42) DPP4PREPFAP
SCHEMBL8254365 0.78 RAB9A (0.45) DPP4PREPFAPALDH1A1
SCHEMBL12324861 0.78 DPP4 (0.41) DPP4PREPFAPDPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 — — US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 — — US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 — — EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 — — EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 — — US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 — — EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 — — WO disclosed
EP-0154353-B1 AN ANTI-AMNESTIC AGENT KABUSHIKI KAISHA YAKULT HONSHA (JP) 1989-11-15 — — EP disclosed
US-4687778-A Anti-amnestic agent KABUSHIKI KAISHA YAKULT HONSHA (JP) 1987-08-18 — — US disclosed
EP-0154353-A2 An anti-amnestic agent KABUSHIKI KAISHA YAKULT HONSHA (JP) 1985-09-11 — — EP disclosed
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