Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25474277 | 0.87 | CYP2C19 (0.63) | CYP2C19APPCYP3A4ALDH1A1NPC1 | |
| SCHEMBL14430061 | 0.74 | MAOB (0.60) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL23792524 | 0.73 | CYP2C19 (0.67) | CYP2C19APPCYP3A4NPC1HPGD | |
| SCHEMBL6412360 | 0.72 | CYP2C19 (0.66) | CYP2C19APPCYP3A4ALDH1A1NPC1 | |
| SCHEMBL5740710 | 0.72 | CYP2C19 (0.66) | CYP2C19APPCYP3A4ALDH1A1NPC1 | |
| SCHEMBL6412358 | 0.72 | CYP2C19 (0.66) | CYP2C19APPCYP3A4ALDH1A1NPC1 | |
| SCHEMBL9408172 | 0.72 | CYP2C19 (0.66) | CYP2C19APPCYP3A4ALDH1A1NPC1 | |
| SCHEMBL11483277 | 0.71 | GPR183 (0.52) | ALDH1A1NPC1RAB9AMAPTMAOA | |
| SCHEMBL11483281 | 0.71 | GPR183 (0.52) | ALDH1A1NPC1RAB9AMAPTMAOA | |
| SCHEMBL29913307 | 0.71 | ENPP2 (0.48) | NPC1RAB9ASMN1; SMN2MAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158102-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CORONAVIRUS INFECTION | PHARMA MAR, S.A. (ES) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158102-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CORONAVIRUS INFECTION | ACE, SARS1, ACE2 | CYP2C19 17/4885APP 1713/4885CYP3A4 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.