Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.56 |
| ▸ | BCKDK | O14874 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.40 |
| ▸ | BAD | Q92934 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL25243752 | 0.99 | MCL1 (0.55) | MCL1BCKDKRXFP1BCL2L1BCL2 | |
| SCHEMBL25217793 | 0.94 | MCL1 (0.57) | MCL1BCKDKRXFP1BCL2L1BCL2 | |
| SCHEMBL25242010 | 0.92 | MCL1 (0.58) | MCL1BCKDKRXFP1BCL2L1BCL2 | |
| SCHEMBL25208186 | 0.90 | BCKDK (0.60) | MCL1BCKDKRXFP1BCL2L1NPC1 | |
| SCHEMBL25245291 | 0.88 | MCL1 (0.53) | MCL1BCKDKRXFP1BCL2L1BCL2 | |
| SCHEMBL25575333 | 0.86 | MCL1 (0.52) | MCL1BCKDKRXFP1BCL2L1BCL2 | |
| Ammonia Solution, Strong SCHEMBL25206491 | 0.85 | MCL1 (0.51) | MCL1BCKDKRXFP1BCL2L1BCL2 | |
| SCHEMBL25203086 | 0.85 | BCKDK (0.60) | MCL1BCKDKRXFP1BCL2L1NPC1 | |
| SCHEMBL25232009 | 0.83 | BCKDK (0.62) | MCL1BCKDKRXFP1BCL2L1NPC1 | |
| SCHEMBL25255060 | 0.83 | MCL1 (0.57) | MCL1BCKDKRXFP1BCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167080-A1 | BCKDK INHIBITORS AND/OR DEGRADERS | PFIZER INC. (US) | 2023-06-01 | — | — | US | disclosed |
| US-20230167080-A1 | BCKDK INHIBITORS AND/OR DEGRADERS | PFIZER INC. (US) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167080-A1 | BCKDK INHIBITORS AND/OR DEGRADERS | BCKDK, KHK, PDK4 | MCL1 2996/4885BCKDK 1/4885RXFP1 3315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.