Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.59 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.59 |
| ▸ | MAP1LC3B | Q9GZQ8 | 4/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | CCNK | O75909 | 1/20 | 0.51 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25180277 | 0.96 | CRBN (0.61) | CRBNDDB1MAP1LC3BSTAT3CCNK | |
| SCHEMBL25359449 | 0.94 | CRBN (0.56) | CRBNDDB1MAP1LC3BSTAT3CCNK | |
| SCHEMBL30526057 | 0.94 | CRBN (0.56) | CRBNDDB1MAP1LC3BSTAT3CCNK | |
| SCHEMBL25362254 | 0.94 | CRBN (0.56) | CRBNDDB1MAP1LC3BSTAT3CCNK | |
| SCHEMBL30526096 | 0.94 | CRBN (0.56) | CRBNDDB1MAP1LC3BSTAT3CCNK | |
| SCHEMBL30135751 | 0.89 | CRBN (0.55) | CRBNDDB1MAP1LC3BIKZF3 | |
| SCHEMBL29259959 | 0.89 | CRBN (0.55) | CRBNDDB1MAP1LC3BIKZF3 | |
| SCHEMBL29165787 | 0.88 | CRBN (0.60) | CRBNDDB1MAP1LC3BSTAT3CCNK | |
| SCHEMBL27314707 | 0.88 | CRBN (0.61) | CRBNDDB1MAP1LC3BSTAT3IKZF3 | |
| SCHEMBL34464156 | 0.88 | CRBN (0.59) | CRBNDDB1MAP1LC3BSTAT3CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088245-A1 | DEGRADATION AGENT AND USE THEREOF | 成都先导药物开发股份有限公司 | 2023-05-25 | — | — | WO | disclosed |