Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | PTGFR | P43088 | 14/20 | 0.73 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.62 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.62 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | PTGIR | P43119 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulprostone SCHEMBL94842 | 0.87 | THRB (1.00) | THRBMEN1KMT2APTGFRPTGER3 | |
| Sulprostone SCHEMBL23353043 | 0.87 | THRB (1.00) | THRBMEN1KMT2APTGFRPTGER3 | |
| Sulprostone SCHEMBL15389929 | 0.87 | THRB (1.00) | THRBMEN1KMT2APTGFRPTGER3 | |
| Sulprostone SCHEMBL23352669 | 0.87 | THRB (1.00) | THRBMEN1KMT2APTGFRPTGER3 | |
| Sulprostone SCHEMBL94843 | 0.87 | THRB (1.00) | THRBMEN1KMT2APTGFRPTGER3 | |
| Sulprostone SCHEMBL23352789 | 0.87 | THRB (1.00) | THRBMEN1KMT2APTGFRPTGER3 | |
| Tiaprost SCHEMBL12708340 | 0.83 | PTGFR (0.78) | THRBPTGFRPTGER3TBXA2RPTGER1 | |
| Tiaprost SCHEMBL14511288 | 0.83 | PTGFR (0.78) | THRBPTGFRPTGER3TBXA2RPTGER1 | |
| Tiaprost SCHEMBL867741 | 0.83 | PTGFR (0.78) | THRBPTGFRPTGER3TBXA2RPTGER1 | |
| Tiaprost SCHEMBL12495592 | 0.83 | PTGFR (0.78) | THRBPTGFRPTGER3TBXA2RPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011133948-A2 | HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME | LONGEVITY BIOTECH, INC. (US) | 2011-10-27 | — | — | WO | disclosed |