Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25575752 | 0.85 | CRBN (0.50) | CRBNDDB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL25905736 | 0.83 | CRBN (0.45) | CRBNDDB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL25074350 | 0.81 | CRBN (0.55) | CRBNDDB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL25122532 | 0.81 | CRBN (0.67) | CRBNDDB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL25575744 | 0.80 | CRBN (0.48) | CRBNDDB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL25214076 | 0.80 | TTR (0.48) | CRBNDDB1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL30267305 | 0.80 | TTR (0.48) | CRBNDDB1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL31607784 | 0.80 | CRBN (0.60) | CRBNDDB1KDM4EMEN1KMT2A | |
| SCHEMBL25123171 | 0.78 | CRBN (0.55) | CRBNDDB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL31105484 | 0.78 | CRBN (0.55) | CRBNDDB1KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393922-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| EP-4328219-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-02-28 | — | — | EP | disclosed |
| EP-4194457-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |