Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25920672 | 0.85 | CRBN (0.43) | CRBNDDB1ALDH1A1 | |
| SCHEMBL25905734 | 0.84 | CRBN (0.42) | CRBNDDB1 | |
| SCHEMBL23065973 | 0.84 | DDB1 (0.52) | CRBNDDB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL30430816 | 0.81 | DDB1 (0.40) | CRBNDDB1KDM4EALDH1A1HTT | |
| SCHEMBL25216832 | 0.81 | DDB1 (0.40) | CRBNDDB1KDM4EALDH1A1HTT | |
| SCHEMBL25905651 | 0.81 | CRBN (0.56) | CRBNDDB1 | |
| SCHEMBL25575759 | 0.81 | CRBN (0.49) | CRBNDDB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL25575745 | 0.80 | CRBN (0.51) | CRBNDDB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL25074350 | 0.78 | CRBN (0.55) | CRBNDDB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL30014315 | 0.78 | DDB1 (0.37) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393922-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| EP-4328219-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-02-28 | — | — | EP | disclosed |
| EP-4194457-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |