Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | CCNK | O75909 | 15/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 15/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 14/20 | 0.44 |
| ▸ | CDK9 | P50750 | 14/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.44 |
| ▸ | CDK2 | P24941 | 13/20 | 0.44 |
| ▸ | CDK7 | P50613 | 7/20 | 0.43 |
| ▸ | CCNH | P51946 | 7/20 | 0.43 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25580806 | 0.95 | JAK1 (0.45) | JAK1CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25581286 | 0.94 | LCK (0.47) | JAK1CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25581350 | 0.90 | CCNK (0.39) | JAK1CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25580804 | 0.90 | CCNE1 (0.47) | JAK1CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25580830 | 0.86 | CCNT1 (0.44) | JAK1CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25581351 | 0.85 | LCK (0.39) | JAK1CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25580838 | 0.85 | CDK7 (0.45) | JAK1CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25581354 | 0.85 | LCK (0.41) | JAK1CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25581443 | 0.85 | LCK (0.41) | JAK1CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25581298 | 0.84 | CCNK (0.47) | JAK1CCNKCDK12CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078451-A1 | COMPOUND USED AS CDK7 KINASE INHIBITOR AND USE THEREOF | 浙江同源康医药股份有限公司 | 2023-05-11 | — | — | WO | disclosed |