Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 16/20 | 0.44 |
| ▸ | CCNK | O75909 | 16/20 | 0.44 |
| ▸ | CDK9 | P50750 | 16/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 16/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.44 |
| ▸ | CDK2 | P24941 | 14/20 | 0.44 |
| ▸ | CDK7 | P50613 | 7/20 | 0.43 |
| ▸ | CCNH | P51946 | 7/20 | 0.43 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.43 |
| ▸ | CD38 | P28907 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25581358 | 0.90 | CCNE1 (0.38) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25581445 | 0.90 | CCNT1 (0.38) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25580838 | 0.86 | CDK7 (0.45) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25580809 | 0.86 | JAK1 (0.46) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25580804 | 0.86 | CCNE1 (0.47) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25580806 | 0.85 | JAK1 (0.45) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25581286 | 0.84 | LCK (0.47) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25580824 | 0.83 | CDK7 (0.51) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25581291 | 0.82 | CLK1 (0.49) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25580832 | 0.82 | CCNT1 (0.51) | CCNT1CCNKCDK9CDK12CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078451-A1 | COMPOUND USED AS CDK7 KINASE INHIBITOR AND USE THEREOF | 浙江同源康医药股份有限公司 | 2023-05-11 | — | — | WO | disclosed |