SCHEMBL25580911

SCHEMBL25580911

CCN(C)CC1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.48
KDM4E B2RXH2 1/20 0.47
PKM P14618 1/20 0.47
GPR119 Q8TDV5 7/20 0.46
LIMK2 P53671 1/20 0.46
RECQL P46063 1/20 0.46
EPHX1 P07099 1/20 0.46
USP2 O75604 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
FAAH O00519 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5570674 0.92 HPGD (0.51) HPGDKDM4EPKMGPR119LIMK2
SCHEMBL1401260 0.88 HPGD (0.53) HPGDKDM4EPKMGPR119LIMK2
SCHEMBL6152127 0.87 HPGD (0.49) HPGDKDM4EPKMGPR119LIMK2
SCHEMBL30085213 0.86 KDM4E (0.48) HPGDKDM4EPKMGPR119LIMK2
SCHEMBL28983622 0.84 KDM4E (0.42) HPGDKDM4EPKMGPR119LIMK2
SCHEMBL7580625 0.83 LIMK2 (0.48) HPGDKDM4EPKMGPR119LIMK2
SCHEMBL26668523 0.82 GPR119 (0.56) KDM4EPKMGPR119LIMK2
SCHEMBL2997902 0.82 LIMK2 (0.51) HPGDKDM4EPKMGPR119LIMK2
SCHEMBL24379125 0.82 HPGD (0.48) HPGDKDM4EPKMGPR119LIMK2
SCHEMBL27391556 0.81 HPGD (0.50) HPGDKDM4EPKMGPR119LIMK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023088245-A1 DEGRADATION AGENT AND USE THEREOF 成都先导药物开发股份有限公司 2023-05-25 WO disclosed